Nope, no difference @Corlove13
The supposed difference is purely one of translation, not of essence, person, or operation. The King James translators used “Holy Ghost” in some verses and “Holy Spirit” in others, but in the original Greek text, there is only one phrase: τὸ πνεῦμα τὸ ἅγιον (to pneuma to hagion), literally “the Holy Spirit.” The word pneuma means breath, wind, or spirit, and it is the same word used in every passage, whether English renders it “Ghost” or “Spirit.” There is not a single manuscript variant that separates the two terms. In Hebrew, the equivalent term is רוּחַ קֹדֶשׁ (ruach qodesh), which again means “Holy Spirit.” The Hebrew verb נָפַח (naphach), used in Genesis 2:7 when God “breathed” into Adam, links directly to Jesus “breathing” on the disciples in John 20:22, where He said λάβετε πνεῦμα ἅγιον (labete pneuma hagion), “receive the Holy Spirit.” It is the same Spirit of God, not a different one.
When Jesus breathed on the disciples, He imparted the regenerating life of the Spirit, preparing them for the empowering outpouring at Pentecost. The verbs used in both moments differ in function, not in identity. In John 20:22, the aorist imperative λάβετε (receive) marks an immediate impartation of divine life, the internal witness of the Spirit, corresponding to new birth. In Acts 1:8, ἐπιλήμψεσθε (you will receive) describes a future empowerment, the Spirit’s external anointing for witness. Same Spirit, different operations.
The Comforter Jesus promised in John 14:16–18 is explicitly identified as the Spirit of truth, and Jesus says, “I will come to you.” This is not a different entity but the same divine presence of Christ through the indwelling Spirit. The Greek word παράκλητος (paraklētos) means advocate or helper. In John 14:26, the same term is used again, and the identity is fixed: ὁ παράκλητος, τὸ πνεῦμα τὸ ἅγιον (the Helper, the Holy Spirit) whom the Father will send in Jesus’ name. No textual distinction allows “Holy Ghost” to refer to Christ Himself and “Holy Spirit” to another person. The Spirit is the Spirit of Christ, proceeding from the Father, bearing witness to the Son, and dwelling within believers.
The early church never read two Spirits or two phases of Spirit identity. At Pentecost, Peter quoted Joel 2:28, אֶשְׁפּוֹךְ אֶת־רוּחִי (I will pour out My Spirit), showing that what was received was the same Spirit Jesus had already breathed, now manifested in fullness and power. The continuity is unbroken: one Spirit, one Lord, one baptism (Ephesians 4:4–6).
Therefore, the English phrase “Holy Ghost” in the KJV is simply an older way of saying “Holy Spirit.” The word “ghost” once meant “spirit” or “breath,” as in “the spirit of man.” Modern translations avoid “ghost” to prevent confusion with the modern meaning of an apparition. Linguistically, the Greek pneuma and Hebrew ruach never split into two divine entities. There is no textual, grammatical, or theological justification for dividing them.
Thus, the “Holy Ghost” and the “Holy Spirit” are the same divine person, the third person of the Trinity, who proceeds from the Father, glorifies the Son, regenerates the believer, and empowers the Church. The verbs differ by context, He is breathed, poured out, fills, empowers, leads, but He Himself is one and the same eternal Spirit of God.
The Holy Spirit
The “Holy Spirit” is spoken of under various titles in the NT (“Spirit” and “Ghost” are renderings of the same word, pneuma; the advantage of the rendering “Spirit” is that it can always be used, whereas “Ghost” always requires the word “Holy” prefixed.) In the following list the omission of the definite article marks its omission in the original (concerning this see below): “Spirit, Mat_22:43; Eternal Spirit, Heb_9:14; the Spirit, Mat_4:1; Holy Spirit, Mat_1:18; the Holy Spirit, Mat_28:19; the Spirit, the Holy, Mat_12:32; the Spirit of promise, the Holy, Eph_1:13; Spirit of God, Rom_8:9; Spirit of (the) living God, 2Co_3:3; the Spirit of God, 1Co_2:11; the Spirit of our God, 1Co_6:11; the Spirit of God, the Holy, Eph_4:30; the Spirit of glory and of God, 1Pe_4:14; the Spirit of Him that raised up Jesus from the dead (i.e., God), Rom_8:11; the Spirit of your Father, Mat_10:20; the Spirit of His Son, Gal_4:6; Spirit of (the) Lord, Act_8:39; the Spirit of (the) Lord, Act_5:9; (the) Lord, (the) Spirit, 2Co_3:18; the Spirit of Jesus, Act_16:7; Spirit of Christ, Rom_8:9; the Spirit of Jesus Christ, Php_1:19; Spirit of adoption, Rom_8:15; the Spirit of truth, Jhn_14:17; the Spirit of life, Rom_8:2; the Spirit of grace, Heb_10:29.”+
- From Notes on Galatians, by Hogg and Vine, p. 193.
J.